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Mitochondrial Dysfunction

Recent studies suggest children with autism spectrum disorders may have metabolic or mitochondrial dysfunction as opposed to metabolic disease. Mitochondria are the main energy-generating machinery in every cell. Nutritional supplementation to improve metabolic processes, including mitochondrial function, may also be helpful for children with Autism Spectrum Disorder.

Please note: These therapies have not been approved by the FDA for the treatment of autism, and should be used only under the supervision of an experienced and knowledgeable health care professional after parents or guardians have received adequate information and given consent.

References:
www.autism.com/treatable/form34qr.htm (accessed April 2008)
Ann Neurol 2005;57:67-81
J Child Neurol. published on-line 2008 Jan 8
Ann NY Acad Sci. 2007 Jun;1107:92-103
Cell Mol Neurobiol. 2004 Apr;24920:219-41
Neuroendocrinology Letters 2002;23:303-8
Dev Brain Dysfunction 1997; 10:40-43
J Inherit Metab Dis. 1993; 16(4):762-770
Pediatrics 1995;95:255-8
J Nutr Env Med 2000;10:25-32
Children with Starving Brains; 2nd Edition, by Jacquelyn McCandless, M.D.